Pleurisy

Pleurisy, also known as pleuritis, is inflammation of the membranes that surround the lungs and line the chest cavity (pleurae). This can result in a sharp chest pain while breathing. Occasionally the pain may be a constant dull ache. Other symptoms may include shortness of breath, cough, fever, or weight loss, depending on the underlying cause. Pleurisy can be caused by a variety of conditions, including viral or bacterial infections, autoimmune disorders, and pulmonary embolism.

Pleurisy
Other namesPleuritis, pleuritic chest pain
Figure A shows normal anatomy. Figure B shows lungs with pleurisy in the right lung, and a pneumothorax of the left lung.
SpecialtyPulmonology
SymptomsSharp chest pain
CausesViral infection, bacterial infection, pneumonia, pulmonary embolism
Diagnostic methodChest X-ray, electrocardiogram (ECG), blood tests
Differential diagnosisPericarditis, heart attack, cholecystitis
TreatmentBased on the underlying cause
MedicationParacetamol (acetaminophen), ibuprofen

The most common cause is a viral infection. Other causes include bacterial infection, pneumonia, pulmonary embolism, autoimmune disorders, lung cancer, following heart surgery, pancreatitis and asbestosis. Occasionally the cause remains unknown. The underlying mechanism involves the rubbing together of the pleurae instead of smooth gliding. Other conditions that can produce similar symptoms include pericarditis, heart attack, cholecystitis, pulmonary embolism, and pneumothorax. Diagnostic testing may include a chest X-ray, electrocardiogram (ECG), and blood tests.

Treatment depends on the underlying cause. Paracetamol (acetaminophen) and ibuprofen may be used to decrease pain. Incentive spirometry may be recommended to encourage larger breaths. About one million people are affected in the United States each year. Descriptions of the condition date from at least as early as 400 BC by Hippocrates.

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