Platelet storage pool deficiency
Platelet storage pool deficiency is a type of coagulopathy characterized by defects in the granules in platelets, particularly a lack of granular non-metabolic adenosine diphosphate. Individuals with adenosine diphosphate deficient storage pool disease present a prolonged bleeding time due to impaired aggregation response to fibrillar collagen.
| Platelet storage pool deficiency | |
|---|---|
| Other names | Storage pool platelet disease |
| Platelet storage pool deficiency is inherited in an autosomal dominant manner | |
| Specialty | Hematology |
| Symptoms | Anemia |
| Causes | Inherited or acquired |
| Diagnostic method | Flow cytometry, Bleeding time analysis |
| Treatment | Antifibrinolytic medications |
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