Piperazine

Piperazine (/pˈpɛrəzn/) is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. Piperazine exists as small alkaline deliquescent crystals with a saline taste.

Piperazine
Names
Preferred IUPAC name
Piperazine
Systematic IUPAC name
1,4-Diazacyclohexane
Other names
Hexahydropyrazine
Piperazidine
Diethylenediamine
1,4-Diazinane
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.003.463
KEGG
UNII
  • InChI=1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2 N
    Key: GLUUGHFHXGJENI-UHFFFAOYSA-N N
  • InChI=1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2
  • C1CNCCN1
Properties
C4H10N2
Molar mass 86.138 g·mol−1
Appearance White crystalline solid
Melting point 106 °C (223 °F; 379 K)
Boiling point 146 °C (295 °F; 419 K) Sublimates
Freely soluble
Acidity (pKa) 9.8
Basicity (pKb) 4.19
-56.8·10−6 cm3/mol
Pharmacology
P02CB01 (WHO)
Pharmacokinetics:
60-70%
Hazards
NFPA 704 (fire diamond)
2
2
0
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

The piperazines are a broad class of chemical compounds, many with important pharmacological properties, which contain a core piperazine functional group.

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