Piperazine
Piperazine (/paɪˈpɛrəziːn/) is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. Piperazine exists as small alkaline deliquescent crystals with a saline taste.
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Names | |||
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Preferred IUPAC name
Piperazine | |||
Systematic IUPAC name
1,4-Diazacyclohexane | |||
Other names
Hexahydropyrazine Piperazidine Diethylenediamine 1,4-Diazinane | |||
Identifiers | |||
3D model (JSmol) |
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ChEBI | |||
ChEMBL | |||
ChemSpider | |||
DrugBank | |||
ECHA InfoCard | 100.003.463 | ||
KEGG | |||
PubChem CID |
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UNII | |||
CompTox Dashboard (EPA) |
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Properties | |||
C4H10N2 | |||
Molar mass | 86.138 g·mol−1 | ||
Appearance | White crystalline solid | ||
Melting point | 106 °C (223 °F; 379 K) | ||
Boiling point | 146 °C (295 °F; 419 K) Sublimates | ||
Freely soluble | |||
Acidity (pKa) | 9.8 | ||
Basicity (pKb) | 4.19 | ||
-56.8·10−6 cm3/mol | |||
Pharmacology | |||
P02CB01 (WHO) | |||
Pharmacokinetics: | |||
60-70% | |||
Hazards | |||
NFPA 704 (fire diamond) | |||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references |
The piperazines are a broad class of chemical compounds, many with important pharmacological properties, which contain a core piperazine functional group.
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