Phytoene synthase
Phytoene synthase (EC 2.5.1.32, prephytoene-diphosphate synthase, 15-cis-phytoene synthase, PSase, geranylgeranyl-diphosphate geranylgeranyltransferase) is a transferase enzyme involved in the biosynthesis of carotenoids. It catalyzes the conversion of geranylgeranyl pyrophosphate to phytoene. This enzyme catalyses the following chemical reaction
- 2 geranylgeranyl diphosphate 15-cis-phytoene + 2 diphosphate (overall reaction)
- (1a) 2 geranylgeranyl diphosphate diphosphate + prephytoene diphosphate
- (1b) prephytoene diphosphate 15-cis-phytoene + diphosphate
| 15-cis-phytoene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.32 | ||||||||
| CAS no. | 50936-61-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme requires Mn2+ for activity. It belongs to squalene/phytoene synthase family of proteins.
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