Phillip Allen Sharp

External videos
External videos
	Meet Phillip Sharp: "What we were able to discover was that in human cells and in many other cells of higher-order organisms, the genes come in discontinuous segments", MIT

Phillip Allen Sharp
Phillip Allen Sharp
	Sharp with the Winthrop-Sears Medal in 2007
Born	June 6, 1944; Falmouth, Kentucky, U.S.
Alma mater	Union College; University of Illinois at Urbana–Champaign;
Spouse	Ann Holcombe (m. 1964)
Children	3
Awards	NAS Award in Molecular Biology (1980); Louisa Gross Horwitz Prize (1988); Dickson Prize (1991); Nobel Prize (1993); Novartis-Drew Award (2003); National Medal of Science (2004);
	Scientific career
Fields	Biologist
Institutions	Caltech; Cold Spring Harbor Laboratory; MIT;
Doctoral students	Connie Cepko; Andrew Fire; Melissa J. Moore; Richard Carthew;
Website	web.mit.edu/sharplab

Phillip Allen Sharp (born June 6, 1944) is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for "the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence". He has been selected to receive the 2015 Othmer Gold Medal.

Sharp's current research focuses on small RNAs and other types of non-coding RNAs. His laboratory works to identify the target mRNAs of microRNAs (miRNAs), and has discovered a class of miRNAs that are produced from sequences adjacent to transcription start sites. His laboratory also studies how miRNA gene regulation functions in angiogenesis and cellular stress.

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