Phenylpropanolamine

Phenylpropanolamine
Clinical data
Trade names	Many
AHFS/Drugs.com	Multum Consumer Information
Pregnancy; category	AU: B2;
Routes of; administration	By mouth
ATC code	R01BA01 (WHO) QG04BX91 (WHO);
Legal status
Legal status	AU: S4 (Prescription only); BR: Class F3 (Prohibited drug precursors); CA: Schedule VI; US: Rx-Only;
Pharmacokinetic data
Metabolism	Hepatic (CYP2D6)
Elimination half-life	2.1–3.4 hours
Identifiers
	IUPAC name (1R,2S)-2-amino-1-phenylpropan-1-ol;
CAS Number	14838-15-4 ;
PubChem CID	10297;
DrugBank	DB00397 ;
ChemSpider	9875 ;
UNII	33RU150WUN;
KEGG	D08368 ;
ChEMBL	ChEMBL136560 ;
CompTox Dashboard (EPA)	DTXSID4023466 ;
ECHA InfoCard	100.035.349
Chemical and physical data
Formula	C9H13NO
Molar mass	151.209 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O[C@H](c1ccccc1)[C@@H](N)C;
	InChI InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m0/s1 ; Key:DLNKOYKMWOXYQA-CBAPKCEASA-N ;
	(verify)

Phenylpropanolamine (PPA) is a sympathomimetic agent which is used as a decongestant and appetite suppressant. It was commonly used in prescription and over-the-counter cough and cold preparations. In veterinary medicine, it is used to control urinary incontinence in dogs.

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