Phenoxybenzamine

Phenoxybenzamine (PBZ, marketed under the trade names Dibenzyline and Dibenyline) is a non-selective, irreversible alpha blocker.

Phenoxybenzamine
Clinical data
Trade namesDibenzyline
AHFS/Drugs.comMonograph
MedlinePlusa682059
Pregnancy
category
  • AU: B2
Routes of
administration
Oral
ATC code
Pharmacokinetic data
Elimination half-life24 hours
Identifiers
  • (RS)-N-Benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.406
Chemical and physical data
FormulaC18H22ClNO
Molar mass303.83 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • ClCCN(C(COc1ccccc1)C)Cc2ccccc2
  • InChI=1S/C18H22ClNO/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17/h2-11,16H,12-15H2,1H3 Y
  • Key:QZVCTJOXCFMACW-UHFFFAOYSA-N Y
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