POLE4

POLE4
Identifiers
Aliases	POLE4, YHHQ1, p12, polymerase (DNA) epsilon 4, accessory subunit, DNA polymerase epsilon 4, accessory subunit
External IDs	OMIM: 607269 MGI: 1914229 HomoloGene: 41339 GeneCards: POLE4
Gene location (Human)
Chr.	Chromosome 2 (human)
End	74,970,128 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	82,682,346 bp
RNA expression pattern
	Top expressed in
	cingulate gyrus; ; popliteal artery; ; monocyte; ; left adrenal gland; ; gastrocnemius muscle; ; left coronary artery; ; prefrontal cortex; ; amygdala; ; thoracic aorta; ; ascending aorta;
	Top expressed in
	secondary oocyte; ; yolk sac; ; retinal pigment epithelium; ; ciliary body; ; iris; ; proximal tubule; ; ureter; ; endocardial cushion; ; barrel cortex; ; neural tube;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; DNA binding; DNA-directed DNA polymerase activity; nucleotidyltransferase activity; protein binding; protein heterodimerization activity;
Cellular component	epsilon DNA polymerase complex; nucleus; nucleoplasm;
Biological process	histone H3 acetylation; DNA biosynthetic process; G1/S transition of mitotic cell cycle; DNA replication initiation; telomere maintenance via semi-conservative replication;
	Sources:Amigo / QuickGO
Orthologs
	56655
	66979
	ENSG00000115350
	ENSMUSG00000030042
	Q9NR33
	Q9CQ36
	NM_019896
	NM_025882; NM_001370295
	NP_063949
	NP_080158; NP_001357224
	Wikidata
View/Edit Human	View/Edit Mouse

Polymerase (DNA-directed), epsilon 4, accessory subunit is a protein that in humans is encoded by the POLE4 gene.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.