POLD2

POLD2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3E0J
Identifiers
Aliases	POLD2, DNA polymerase delta 2, accessory subunit
External IDs	OMIM: 600815 MGI: 1097163 HomoloGene: 4538 GeneCards: POLD2
Gene location (Human)
Chr.	Chromosome 7 (human)
End	44,124,358 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	5,828,292 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; right lobe of liver; ; body of pancreas; ; skin of abdomen; ; ganglionic eminence; ; anterior pituitary; ; gastrocnemius muscle; ; left uterine tube; ; tibial nerve; ; popliteal artery;
	Top expressed in
	yolk sac; ; internal carotid artery; ; maxillary prominence; ; external carotid artery; ; medial ganglionic eminence; ; abdominal wall; ; primitive streak; ; dermis; ; endocardial cushion; ; neural tube;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; DNA-directed DNA polymerase activity;
Cellular component	nucleoplasm; nucleus; delta DNA polymerase complex;
Biological process	nucleotide-excision repair, DNA gap filling; DNA replication; translesion synthesis; transcription-coupled nucleotide-excision repair; nucleotide-excision repair, DNA incision; telomere maintenance; nucleotide-excision repair, DNA incision, 5'-to lesion; DNA repair; DNA strand elongation involved in DNA replication; cellular response to DNA damage stimulus; telomere maintenance via semi-conservative replication; DNA mismatch repair; DNA biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	5425
	18972
	ENSG00000106628
	ENSMUSG00000020471
	P49005
	O35654
	NM_001127218; NM_001256879; NM_006230
	NM_008894; NM_001361942
	NP_001120690; NP_001243808; NP_006221
	NP_032920; NP_001348871
	Wikidata
View/Edit Human	View/Edit Mouse

DNA polymerase delta subunit 2 is an enzyme that in humans is encoded by the POLD2 gene. It is a component of the DNA polymerase delta complex.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.