Phospholipase D₁

PLD1
Identifiers
Aliases	PLD1, phospholipase D1, CVDD
External IDs	OMIM: 602382 MGI: 109585 HomoloGene: 116234 GeneCards: PLD1
Gene location (Human)
Chr.	Chromosome 3 (human)
End	171,810,950 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	28,187,511 bp
RNA expression pattern
	Top expressed in
	gallbladder; ; duodenum; ; left adrenal gland; ; corpus callosum; ; skin of abdomen; ; jejunal mucosa; ; gums; ; epithelium of esophagus; ; secondary oocyte; ; rectum;
	Top expressed in
	secondary oocyte; ; crypt of lieberkuhn of small intestine; ; jejunum; ; ileum; ; left colon; ; Paneth cell; ; duodenum; ; submandibular gland; ; gastric mucosa; ; carotid body;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	phospholipase D activity; N-acylphosphatidylethanolamine-specific phospholipase D activity; protein binding; catalytic activity; phosphatidylinositol binding; hydrolase activity;
Cellular component	cytoplasm; late endosome membrane; Golgi membrane; endocytic vesicle; lysosomal membrane; apical plasma membrane; endoplasmic reticulum; perinuclear region of cytoplasm; endosome; endoplasmic reticulum membrane; membrane; Golgi apparatus; plasma membrane; specific granule membrane; tertiary granule membrane; cholinergic synapse;
Biological process	regulation of microvillus assembly; lipid metabolism; cell motility; small GTPase mediated signal transduction; lipid catabolic process; chemotaxis; Ras protein signal transduction; neutrophil degranulation; phosphatidic acid biosynthetic process; inositol lipid-mediated signaling; regulation of synaptic vesicle cycle;
	Sources:Amigo / QuickGO
Orthologs
	5337
	18805
	ENSG00000075651
	ENSMUSG00000027695
	Q13393
	Q9Z280
	NM_001130081; NM_002662
	NM_001164056; NM_008875; NM_001368667
	NP_001123553; NP_002653
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Phospholipase D₁ (PLD1) is an enzyme that in humans is encoded by the PLD1 gene, though analogues are found in plants, fungi, prokaryotes, and even viruses.

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Phospholipase D1

Phospholipase D₁