PER2

PER2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3GDI, 4CT0, 4U8H
Identifiers
Aliases	PER2, FASPS, FASPS1, period circadian clock 2, period circadian regulator 2
External IDs	OMIM: 603426 MGI: 1195265 HomoloGene: 7885 GeneCards: PER2
Gene location (Human)
Chr.	Chromosome 2 (human)
End	238,290,102 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	91,387,046 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; bronchial epithelial cell; ; palpebral conjunctiva; ; urethra; ; caput epididymis; ; lactiferous duct; ; gums; ; hair follicle; ; tibia;
	Top expressed in
	adrenal gland; ; left lung lobe; ; suprachiasmatic nucleus; ; rectum; ; lacrimal gland; ; median eminence; ; primary motor cortex; ; respiratory epithelium; ; olfactory epithelium; ; cerebellar vermis;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transcription coactivator activity; transcription cis-regulatory region binding; protein binding; transcription corepressor binding; transcription factor binding;
Cellular component	nucleolus; perinuclear region of cytoplasm; nucleus; cytoplasm;
Biological process	histone H3 deacetylation; gluconeogenesis; regulation of transcription, DNA-templated; regulation of insulin secretion; rhythmic process; negative regulation of fat cell proliferation; negative regulation of circadian rhythm; negative regulation of transcription by RNA polymerase II; circadian regulation of gene expression; transcription, DNA-templated; fatty acid metabolic process; regulation of cell cycle; negative regulation of protein ubiquitination; circadian regulation of translation; response to ischemia; regulation of vasoconstriction; glycogen biosynthetic process; negative regulation of transcription regulatory region DNA binding; regulation of circadian rhythm; circadian rhythm; white fat cell differentiation; regulation of glutamate uptake involved in transmission of nerve impulse; lactate biosynthetic process; negative regulation of transcription, DNA-templated; regulation of neurogenesis; positive regulation of nucleic acid-templated transcription; response to light stimulus; entrainment of circadian clock by photoperiod; positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	8864
	18627
	ENSG00000132326
	ENSMUSG00000055866
	O15055
	O54943
	NM_003894; NM_022817
	NM_011066
	NP_073728
	NP_035196
	Wikidata
View/Edit Human	View/Edit Mouse

PER2 is a protein in mammals encoded by the PER2 gene. PER2 is noted for its major role in circadian rhythms.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.