PDPN

PDPN
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3WSR, 4YO0
Identifiers
Aliases	PDPN, AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A, podoplanin, D2-40
External IDs	OMIM: 608863 MGI: 103098 HomoloGene: 4729 GeneCards: PDPN
Gene location (Human)
Chr.	Chromosome 1 (human)
End	13,617,957 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	143,026,134 bp
RNA expression pattern
	Top expressed in
	tibia; ; germinal epithelium; ; retinal pigment epithelium; ; secondary oocyte; ; ganglionic eminence; ; gallbladder; ; gastric mucosa; ; parietal pleura; ; left uterine tube; ; canal of the cervix;
	Top expressed in
	yolk sac; ; lung; ; urinary bladder; ; blastocyst; ; secondary oocyte; ; ovary; ; lens; ; neural tube; ; mesencephalon; ; white adipose tissue;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	folic acid transmembrane transporter activity; water channel activity; amino acid transmembrane transporter activity; water transmembrane transporter activity; signaling receptor binding; protein binding; chaperone binding; chemokine binding;
Cellular component	integral component of membrane; integral component of plasma membrane; plasma membrane; membrane; tetraspanin-enriched microdomain; lamellipodium membrane; cytoplasmic vesicle; filopodium membrane; microvillus membrane; ruffle membrane; cell projection; leading edge of lamellipodium; cytoplasm; cytosol; basolateral plasma membrane; apical plasma membrane; cell junction; membrane raft; ruffle; lamellipodium; filopodium;
Biological process	folic acid transport; water transport; platelet activation; multicellular organism development; regulation of cell shape; amino acid transport; positive regulation of epithelial to mesenchymal transition; positive regulation of cell migration; Rho protein signal transduction; wound healing, spreading of cells; positive regulation of extracellular matrix disassembly; regulation of lamellipodium morphogenesis; cell morphogenesis; lymphangiogenesis; negative regulation of cell population proliferation; lung development; negative regulation of apoptotic process; lymph node development; lymphatic endothelial cell fate commitment; actin-mediated cell contraction; regulation of substrate adhesion-dependent cell spreading; positive regulation of platelet aggregation; regulation of myofibroblast contraction; amino acid transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	10630
	14726
	ENSG00000162493
	ENSMUSG00000028583
	Q86YL7
	Q62011
NM_001006624; NM_001006625; NM_006474; NM_198389; NM_001385053;
	NM_013317
	NM_001290822; NM_010329
	NP_001006625; NP_001006626; NP_006465; NP_938203
	NP_001277751; NP_034459
	Wikidata
View/Edit Human	View/Edit Mouse

Podoplanin is a protein that in humans is encoded by the PDPN gene.

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