PCSK5

PCSK5
Identifiers
Aliases	PCSK5, PC5, PC6, PC6A, SPC6, proprotein convertase subtilisin/kexin type 5
External IDs	OMIM: 600488 MGI: 97515 HomoloGene: 21244 GeneCards: PCSK5
Gene location (Human)
Chr.	Chromosome 9 (human)
End	76,362,975 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	17,814,996 bp
RNA expression pattern
	Top expressed in
	saphenous vein; ; sural nerve; ; pericardium; ; pancreatic ductal cell; ; secondary oocyte; ; visceral pleura; ; duodenum; ; parietal pleura; ; jejunal mucosa; ; urethra;
	Top expressed in
	external carotid artery; ; internal carotid artery; ; Paneth cell; ; vas deferens; ; adrenal gland; ; body of femur; ; molar; ; left lung lobe; ; fossa; ; cumulus cell;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	serine-type endopeptidase activity; peptidase activity; hydrolase activity; serine-type peptidase activity; peptide binding; protein binding; endopeptidase activity;
Cellular component	integral component of membrane; endomembrane system; Golgi lumen; membrane; secretory granule; Golgi apparatus; extracellular region; extracellular space; trans-Golgi network; integral component of Golgi membrane;
Biological process	viral life cycle; proteolysis; female pregnancy; cell-cell signaling; coronary vasculature development; renin secretion into blood stream; heart development; cardiac septum development; determination of left/right symmetry; protein processing; signal peptide processing; limb morphogenesis; respiratory tube development; peptide biosynthetic process; embryo implantation; peptide hormone processing; kidney development; embryonic skeletal system development; embryonic digestive tract development; anterior/posterior pattern specification; regulation of lipoprotein lipase activity; nerve growth factor processing;
	Sources:Amigo / QuickGO
Orthologs
	5125
	18552
	ENSG00000099139
	ENSMUSG00000024713
	Q92824
	Q04592
	NM_001190482; NM_006200; NM_001372043
	NM_001163144; NM_001190483
	NP_001177411; NP_006191; NP_001358972
	NP_001156616; NP_001177412
	Wikidata
View/Edit Human	View/Edit Mouse

Proprotein convertase subtilisin/kexin type 5 is an enzyme that in humans is encoded by the PCSK5 gene, found in chromosome 9q21.3 Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.

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