PAX5

PAX5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1K78, 1MDM
Identifiers
Aliases	PAX5, ALL3, BSAP, paired box 5, PAX-5
External IDs	OMIM: 167414 MGI: 97489 HomoloGene: 56419 GeneCards: PAX5
Gene location (Human)
Chr.	Chromosome 9 (human)
End	37,034,268 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	44,710,487 bp
RNA expression pattern
	Top expressed in
	lymph node; ; appendix; ; bone marrow cells; ; spleen; ; blood; ; thymus; ; spongy bone; ; superficial temporal artery; ; superior surface of tongue; ; periodontal fiber;
	Top expressed in
	spleen; ; blood; ; female urethra; ; substantia nigra; ; secondary oocyte; ; subcutaneous adipose tissue; ; bone marrow; ; thymus; ; rhombic lip; ; body of femur;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; fibrillar center; cytosol; intracellular membrane-bounded organelle; nucleoplasm;
Biological process	cell differentiation; regulation of transcription, DNA-templated; lateral ventricle development; human ageing; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; nervous system development; multicellular organism development; adult behavior; humoral immune response; spermatogenesis; negative regulation of histone H3-K9 methylation; cerebral cortex development; animal organ morphogenesis; skeletal muscle cell differentiation; embryonic cranial skeleton morphogenesis; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; regulation of B cell receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	5079
	18507
	ENSG00000196092
	ENSMUSG00000014030
	Q02548
	Q02650
NM_001280547; NM_001280548; NM_001280549; NM_001280550; NM_001280551;
	NM_001280552; NM_001280553; NM_001280554; NM_001280555; NM_001280556; NM_016734
	NM_008782
NP_001267476; NP_001267477; NP_001267478; NP_001267479; NP_001267480;
	NP_001267481; NP_001267482; NP_001267483; NP_001267484; NP_001267485; NP_057953; NP_001267480.1
	NP_032808
	Wikidata
View/Edit Human	View/Edit Mouse

Paired box protein Pax-5 is a protein that in humans is encoded by the PAX5 gene.

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