Oxilofrine

Oxilofrine (also known as methylsynephrine, hydroxyephrine, oxyephrine, and 4-HMP) is a substituted phenethylamine stimulant drug chemically related to ephedrine and to synephrine.

Oxilofrine
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • (1S*,2R*)-(±)-4-(1-Hydroxy-2-methylamino-propyl)phenol
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.067
Chemical and physical data
FormulaC10H15NO2
Molar mass181.235 g·mol−1
  • InChI=1S/C10H15NO2/c1-7(11-2)10(13)8-3-5-9(12)6-4-8/h3-7,10-13H,1-2H3 Y
  • Key:OXFGTKPPFSCSMA-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

Oxilofrine is currently a World Anti-Doping Agency (WADA) prohibited substance when used in competition. It has been found as an adulterant in some dietary supplements. Even after receiving warning letters from the FDA, some sports and weight loss supplement companies continue to use oxilofrine as an undeclared ingredient in their products despite it being prohibited.

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