OSR2 (gene)

OSR2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EE8
Identifiers
Aliases	OSR2, odd-skipped related transciption factor 2
External IDs	OMIM: 611297 MGI: 1930813 HomoloGene: 14200 GeneCards: OSR2
Gene location (Human)
Chr.	Chromosome 8 (human)
End	98,952,104 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	35,303,451 bp
RNA expression pattern
	Top expressed in
	palpebral conjunctiva; ; canal of the cervix; ; left uterine tube; ; seminal vesicula; ; urethra; ; right uterine tube; ; nipple; ; oocyte; ; caput epididymis; ; endometrium;
	Top expressed in
	uterus; ; ileum; ; intestinal villus; ; vas deferens; ; eyelid; ; jejunum; ; esophagus; ; glomerulus; ; cervix; ; crypt of lieberkuhn of small intestine;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; protein binding; nucleic acid binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding;
Cellular component	nucleus;
Biological process	negative regulation of transcription by RNA polymerase II; metanephros development; mesonephros development; chondrocyte differentiation; positive regulation of cell population proliferation; positive regulation of gene expression; cell differentiation; positive regulation of bone mineralization; osteoblast proliferation; embryonic forelimb morphogenesis; embryonic hindlimb morphogenesis; embryonic skeletal limb joint morphogenesis; middle ear morphogenesis; odontogenesis; embryonic digit morphogenesis; positive regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; embryonic skeletal system morphogenesis; positive regulation of epithelial cell proliferation; roof of mouth development; embryonic skeletal joint morphogenesis; head development; bone morphogenesis; eyelid development in camera-type eye; embryonic skeletal joint development; embryo development ending in birth or egg hatching; urogenital system development;
	Sources:Amigo / QuickGO
Orthologs
	116039
	107587
	ENSG00000164920
	ENSMUSG00000022330
	Q8N2R0
	Q91ZD1
	NM_001142462; NM_001286841; NM_053001; NM_001394683
	NM_054049; NM_001368665
	NP_001135934; NP_001273770; NP_443727
	NP_473390; NP_001355594
	Wikidata
View/Edit Human	View/Edit Mouse

Protein odd-skipped-related 2 is a protein that in humans is encoded by the OSR2 gene. In mice, it is involved in the development of the palate and in suppressing the formation of teeth after the eruption of adult teeth.

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