Solute carrier organic anion transporter family member 1A2

SLCO1A2
Identifiers
Aliases	SLCO1A2, OATP, OATP-A, OATP1A2, SLC21A3, solute carrier organic anion transporter family member 1A2
External IDs	OMIM: 602883 MGI: 1351865 HomoloGene: 56603 GeneCards: SLCO1A2
Gene location (Human)
Chr.	Chromosome 12 (human)
End	21,419,594 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	142,268,707 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; amygdala; ; optic nerve; ; putamen; ; substantia nigra; ; hypothalamus; ; caudate nucleus; ; hippocampus proper; ; Brodmann area 9; ; nucleus accumbens;
	Top expressed in
	seminal vesicula; ; stria vascularis; ; salivary gland; ; choroid plexus; ; olfactory epithelium; ; submandibular gland; ; lacrimal gland; ; parotid gland; ; morula; ; secondary oocyte;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transporter activity; organic anion transmembrane transporter activity; bile acid transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane;
Biological process	ion transport; organic anion transport; bile acid and bile salt transport; sodium-independent organic anion transport; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	6579
	108096
	ENSG00000084453
	ENSMUSG00000063975
	P46721
	Q91YY5
	NM_005075; NM_021094; NM_134431
	NM_001267707; NM_130861
	NP_066580; NP_602307
	NP_001254636; NP_570931
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier organic anion transporter family member 1A2 is a protein that in humans is encoded by the SLCO1A2 gene.

This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.

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