Nyasol

Nyasol, also known as cis-hinokiresinol or as (Z)-hinokiresinol, is a lignan that is found in Anemarrhena asphodeloides. It has estrogenic activity, acting as a selective agonist of the ERβ, and hence is a phytoestrogen. In addition, (-)-nyasol has been found to inhibit the production of eicosanoids and nitric oxide in vitro and shows anti-inflammatory effects.

Nyasol
Names
IUPAC name
4,4'-[(1Z,3R)-3-Ethenyl-1-propene-1,3-diyl]bis[phenol]
Other names
cis-Hinokiresinol; (Z)-Hinokiresinol
Identifiers
3D model (JSmol)
UNII
  • InChI=1S/C17H16O2/c1-2-14(15-7-11-17(19)12-8-15)6-3-13-4-9-16(18)10-5-13/h2-12,14,18-19H,1H2/b6-3-/t14-/m1/s1
    Key: VEAUNWQYYMXIRB-JHAQOBCDSA-N
  • C=C[C@H](/C=C\C1=CC=C(C=C1)O)C2=CC=C(C=C2)O
Properties
C17H16O2
Molar mass 252.313 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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