Nitrous oxide
Names | |
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IUPAC names
Nitrous oxide (not recommended) Dinitrogen oxide (alternative name) | |
Systematic IUPAC name
Oxodiazen-2-ium-1-ide | |
Other names
Laughing gas, sweet air, nitrous, nos, protoxide of nitrogen, hyponitrous oxide, dinitrogen oxide, dinitrogen monoxide | |
Identifiers | |
3D model (JSmol) |
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8137358 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.030.017 |
E number | E942 (glazing agents, ...) |
2153410 | |
KEGG | |
PubChem CID |
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RTECS number |
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UNII | |
UN number | 1070 (compressed) 2201 (liquid) |
CompTox Dashboard (EPA) |
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Properties | |
N 2O | |
Molar mass | 44.013 g/mol |
Appearance | colourless gas |
Density | 1.977 g/L (gas) |
Melting point | −90.86 °C (−131.55 °F; 182.29 K) |
Boiling point | −88.48 °C (−127.26 °F; 184.67 K) |
1.5 g/L (15 °C) | |
Solubility | soluble in alcohol, ether, sulfuric acid |
log P | 0.35 |
Vapor pressure | 5150 kPa (20 °C) |
−18.9·10−6 cm3/mol | |
Refractive index (nD) |
1.000516 (0 °C, 101.325 kPa) |
Viscosity | 14.90 μPa·s |
Structure | |
linear, C∞v | |
0.166 D | |
Thermochemistry | |
Std molar entropy (S⦵298) |
219.96 J/(K·mol) |
Std enthalpy of formation (ΔfH⦵298) |
+82.05 kJ/mol |
Pharmacology | |
N01AX13 (WHO) | |
Inhalation | |
Pharmacokinetics: | |
0.004% | |
5 minutes | |
Respiratory | |
Hazards | |
GHS labelling: | |
Danger | |
H270, H280, H281 | |
P220, P244, P282, P317, P336, P370+P376, P403, P410+P403 | |
NFPA 704 (fire diamond) | |
Flash point | Nonflammable |
Safety data sheet (SDS) | Ilo.org, ICSC 0067 |
Related compounds | |
Nitric oxide Dinitrogen trioxide Nitrogen dioxide Dinitrogen tetroxide Dinitrogen pentoxide | |
Related compounds |
Ammonium nitrate Azide |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references |
Nitrous oxide (dinitrogen oxide or dinitrogen monoxide), commonly known as laughing gas, nitrous, nitro, or nos, is a chemical compound, an oxide of nitrogen with the formula N
2O. At room temperature, it is a colourless non-flammable gas, and has a slightly sweet scent and taste. At elevated temperatures, nitrous oxide is a powerful oxidiser similar to molecular oxygen.
Nitrous oxide has significant medical uses, especially in surgery and dentistry, for its anaesthetic and pain-reducing effects. Its colloquial name, "laughing gas", coined by Humphry Davy, is due to the euphoric effects upon inhaling it, a property that has led to its recreational use as a dissociative anaesthetic. It is on the World Health Organization's List of Essential Medicines. It is also used as an oxidiser in rocket propellants, and in motor racing to increase the power output of engines.
Nitrous oxide's atmospheric concentration reached 333 parts per billion (ppb) in 2020, increasing at a rate of about 1 ppb annually. It is a major scavenger of stratospheric ozone, with an impact comparable to that of CFCs. Global accounting of N
2O sources and sinks over the decade ending 2016 indicates that about 40% of the average 17 TgN/yr (teragrams, or million metric tons, of nitrogen per year) of emissions originated from human activity, and shows that emissions growth chiefly came from expanding agriculture. Being the third most important greenhouse gas, nitrous oxide also substantially contributes to global warming.
Nitrous oxide is used as a propellant, and has a variety of applications from rocketry to making whipped cream. It is used as a recreational drug for its potential to induce a brief "high". Most recreational users are unaware of its neurotoxic effects when abused. When used chronically, nitrous oxide has the potential to cause neurological damage through inactivation of vitamin B12.