Nitisinone

Nitisinone
Clinical data
Trade names	Nityr, Orfadin
Other names	NTBC
AHFS/Drugs.com	Professional Drug Facts
License data	EU EMA: by INN; US DailyMed: Nitisinone; US FDA: Nitisinone;
Routes of; administration	By mouth
ATC code	A16AX04 (WHO) ;
Legal status
Legal status	US: ℞-only; EU: Rx-only;
Pharmacokinetic data
Elimination half-life	Approximately 54 h
Identifiers
	IUPAC name 2-[2-nitro-4-(trifluoromethyl)benzoyl]; cyclohexane-1,3-dione;
CAS Number	104206-65-7 ;
PubChem CID	115355;
IUPHAR/BPS	6834;
DrugBank	DB00348 ;
ChemSpider	103195 ;
UNII	K5BN214699;
KEGG	D05177 ;
ChEBI	CHEBI:50378 ;
ChEMBL	ChEMBL1337 ;
CompTox Dashboard (EPA)	DTXSID9042673 ;
ECHA InfoCard	100.218.521
Chemical and physical data
Formula	C14H10F3NO5
Molar mass	329.231 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(c1ccc(cc1[N+]([O-])=O)C(F)(F)F)C2C(=O)CCCC2=O;
	InChI InChI=1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,12H,1-3H2 ; Key:OUBCNLGXQFSTLU-UHFFFAOYSA-N ;
	(verify)

Nitisinone, sold under the brand name Orfadin among others, is a medication used to slow the effects of hereditary tyrosinemia type 1 (HT-1).

It is available as a generic medication.

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