Neramexane

Neramexane
Clinical data
ATC code	none;
Identifiers
	IUPAC name 1,3,3,5,5-pentamethylcyclohexanamine;
CAS Number	219810-59-0 ;
PubChem CID	6433106;
ChemSpider	4938294 ;
UNII	856DX0KJ84;
CompTox Dashboard (EPA)	DTXSID40176399 ;
ECHA InfoCard	100.107.752
Chemical and physical data
Formula	C11H23N
Molar mass	169.312 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1(C)(N)CC(C)(C)CC(C)(C)C1;
	InChI InChI=1S/C11H23N/c1-9(2)6-10(3,4)8-11(5,12)7-9/h6-8,12H2,1-5H3 ; Key:OGZQTTHDGQBLBT-UHFFFAOYSA-N ;
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Neramexane is a drug related to memantine, which acts as an NMDA antagonist and has neuroprotective effects. It is being developed for various possible applications, including treatment of tinnitus, Alzheimer's disease, drug addiction and as an analgesic. Animal studies have also suggested antidepressant and nootropic actions, so there are a wide range of potential applications this drug may be used for. It also acts as a nicotinic acetylcholine receptor antagonist.

A clinical trial found that doses of 50 mg and above safely improved tinnitus scores over 16 weeks.

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