Niece and nephew
In the lineal kinship system used in the English-speaking world, a niece or nephew is a child of an individual's sibling or sibling-in-law. A niece is female and a nephew is male, and they would call their parents' siblings aunt or uncle. The gender-neutral term nibling has been used in place of the common terms, especially in specialist literature.
Look up niece in Wiktionary, the free dictionary.
Look up nephew in Wiktionary, the free dictionary.
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As aunt/uncle and niece/nephew are separated by one generation, they are an example of a second-degree relationship. They are 25% related by blood, unless related by marriage.
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