Sialidase-1

NEU1
Identifiers
Aliases	NEU1, NANH, NEU, SIAL1, neuraminidase 1 (lysosomal sialidase), neuraminidase 1
External IDs	OMIM: 608272 MGI: 97305 HomoloGene: 375 GeneCards: NEU1
Gene location (Human)
Chr.	Chromosome 6 (human)
End	31,862,905 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	35,154,929 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; bone marrow cells; ; left adrenal gland; ; placenta; ; gallbladder; ; kidney; ; duodenum; ; renal cortex; ; stromal cell of endometrium; ; pituitary gland;
	Top expressed in
	kidney; ; proximal tubule; ; ileum; ; seminal vesicula; ; yolk sac; ; gallbladder; ; left colon; ; epithelium of stomach; ; cingulate gyrus; ; superior frontal gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	exo-alpha-(2->3)-sialidase activity; exo-alpha-(2->8)-sialidase activity; exo-alpha-(2->6)-sialidase activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; exo-alpha-sialidase activity; protein binding; alpha-sialidase activity;
Cellular component	cytoplasmic vesicle; intracellular membrane-bounded organelle; lysosomal membrane; extracellular exosome; lysosome; plasma membrane; lysosomal lumen; cell junction; membrane; extracellular region; specific granule lumen; cytoplasm;
Biological process	ganglioside catabolic process; lipid catabolic process; lipid metabolism; metabolism; oligosaccharide catabolic process; glycosphingolipid metabolic process; neutrophil degranulation; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	4758
	18010
ENSG00000227129; ENSG00000184494; ENSG00000223957; ENSG00000234846; ENSG00000204386;
	ENSG00000234343; ENSG00000227315; ENSG00000228691
	ENSMUSG00000007038
	Q99519
	O35657
	NM_000434
	NM_010893
	NP_000425
	NP_035023
	Wikidata
View/Edit Human	View/Edit Mouse

Sialidase-1, is a mammalian lysosomal neuraminidase enzyme which in humans is encoded by the NEU1 gene.

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