N-Formylmethionine

N-Formylmethionine
Names
	IUPAC name N-Formylmethionine
	Systematic IUPAC name (S)-2-Formylamino-4-methylsulfanylbutanoic acid
	Other names 2-Formylamino-4-methylsulfanyl-butyric acid; Formylmethionine; N-Formyl(methyl)homocysteine
Identifiers
CAS Number	4289-98-9 ;
3D model (JSmol)	Interactive image;
Abbreviations	fMet
ChEBI	CHEBI:182822;
ChemSpider	887;
EC Number	224-322-8;
PubChem CID	911;
UNII	PS9357B4XH ;
	InChI InChI=1S/C6H11NO3S/c1-11-3-2-5(6(9)10)7-4-8/h4-5H,2-3H2,1H3,(H,7,8)(H,9,10) Key: PYUSHNKNPOHWEZ-UHFFFAOYSA-N;
	SMILES CSCC[C@H](NC=O)C(O)=O;
Properties
Chemical formula	C6H11NO3S
Molar mass	177.22 g/mol
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H319
Precautionary statements	P264+P265, P280, P305+P351+P338, P337+P317
Supplementary data page
	N-Formylmethionine (data page)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

N-Formylmethionine (fMet, HCO-Met, For-Met) is a derivative of the amino acid methionine in which a formyl group has been added to the amino group. It is specifically used for initiation of protein synthesis from bacterial and organellar genes, and may be removed post-translationally.

fMet plays a crucial part in the protein synthesis of bacteria, mitochondria and chloroplasts. It is not used in cytosolic protein synthesis of eukaryotes, where eukaryotic nuclear genes are translated. It is also not used by Archaea. In the human body, fMet is recognized by the immune system as foreign material, or as an alarm signal released by damaged cells, and stimulates the body to fight against potential infection.

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