Minoxidil

Minoxidil
Clinical data
Trade names	Loniten, Rogaine, others
Other names	2,4-Diamino-6-piperidinopyrimidine 3-oxide
AHFS/Drugs.com	Monograph
MedlinePlus	a682608
License data	US DailyMed: Minoxidil;
Pregnancy; category	AU: C;
Routes of; administration	By mouth, topical
ATC code	C02DC01 (WHO) D11AX01 (WHO);
Legal status
Legal status	AU: S4 (Prescription only) / S2; UK: General sales list (GSL, OTC) / POM; US: WARNINGOTC / Rx-only;
Pharmacokinetic data
Metabolism	Primarily liver
Elimination half-life	4.2 h
Excretion	Kidney
Identifiers
	IUPAC name 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine;
CAS Number	38304-91-5 ;
PubChem CID	4201;
IUPHAR/BPS	4254;
DrugBank	DB00350 ;
ChemSpider	10438564 ;
UNII	5965120SH1;
KEGG	D00418 ;
ChEBI	CHEBI:6942 ;
ChEMBL	ChEMBL802 ;
PDB ligand	MXD (PDBe, RCSB PDB);
CompTox Dashboard (EPA)	DTXSID9040685 ;
ECHA InfoCard	100.048.959
Chemical and physical data
Formula	C9H15N5O
Molar mass	209.253 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	248 °C (478 °F)
Solubility in water	<1
	SMILES Nc1cc(nc(N)[n+]1[O-])N2CCCCC2;
	InChI InChI=1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6H,1-5,10H2,(H2,11,12) ; Key:ZFMITUMMTDLWHR-UHFFFAOYSA-N ;
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Minoxidil is a medication used for the treatment of high blood pressure and pattern hair loss. It is an antihypertensive and a vasodilator. It is available as a generic medication by prescription in oral tablet form and over the counter as a topical liquid or foam.

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