Metyrapone

Metyrapone, sold under the brand name Metopirone, is a medication which is used in the diagnosis of adrenal insufficiency and occasionally in the treatment of Cushing's syndrome (hypercortisolism). It is part of the steroidogenesis inhibitor class of drugs.

Metyrapone
Clinical data
Trade namesMetopirone
AHFS/Drugs.comConsumer Drug Information
Pregnancy
category
Routes of
administration
By mouth
ATC code
Pharmacokinetic data
Elimination half-life1.9 ± 0.7 hours
Identifiers
  • 2-methyl-1,2-di(pyridin-3-yl)propan-1-one
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.188
Chemical and physical data
FormulaC14H14N2O
Molar mass226.279 g·mol−1
3D model (JSmol)
  • O=C(c1cccnc1)C(c2cccnc2)(C)C
  • InChI=1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3 Y
  • Key:FJLBFSROUSIWMA-UHFFFAOYSA-N Y
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