N-Methylephedrine
N-Methylephedrine is a derivative of ephedrine. It has been isolated from Ephedra distachya.
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IUPAC name
(1R,2S)-2-(Dimethylamino)-1-phenyl-1-propanol | |
Other names
N-Methyl-L-ephedrine | |
Identifiers | |
3D model (JSmol) |
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ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.008.203 |
KEGG | |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C11H17NO | |
Molar mass | 179.263 g·mol−1 |
Melting point | 87 to 87.5 °C (188.6 to 189.5 °F; 360.1 to 360.6 K) 192 °C (HCl) |
Readily soluble | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references |
In organic chemistry, N-methylephedrine is used as a resolving agent and as a precursor to chiral supporting electrolytes, phase-transfer catalysts, and reducing agents. Pharmacologically, N-methylephedrine is a non-selective adrenergic receptor agonist.
Just like ephedrine, it may have abuse potential . N-methylephedrine is one of the four constituents of BRON, a Japanese OTC cough medicine with reports of abuse. Addiction liability of BRON was attributed primarily to the Codeine component.
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