Methyl fluoroacetate

Methyl fluoroacetate (MFA) is an extremely toxic methyl ester of fluoroacetic acid. It is a colorless, odorless liquid at room temperature. It is used as a laboratory chemical and as a rodenticide. Because of its extreme toxicity, MFA was studied for potential use as a chemical weapon.

Methyl fluoroacetate
Names
Preferred IUPAC name
Methyl fluoroacetate
Other names
MFA
TL-551
AF-1
T-1202
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.006.563
EC Number
  • 207-218-7
UNII
  • InChI=1S/C3H5FO2/c1-6-3(5)2-4/h2H2,1H3
    Key: RJBYSQHLLIHSLT-UHFFFAOYSA-N
  • COC(=O)CF
Properties
C3H5FO2
Molar mass 92.069 g·mol−1
Appearance Colorless liquid
Melting point −40 °C (−40 °F; 233 K)
Boiling point 104 °C (219 °F; 377 K)
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Extremely toxic
GHS labelling:
Danger
H226, H300, H315, H319, H335, H400
P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P273, P280, P301+P310, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P370+P378, P391, P403+P233, P403+P235, P405, P501
Flash point −32 °C (−26 °F; 241 K)
Lethal dose or concentration (LD, LC):
6 mg/kg (mice)
Related compounds
Related compounds
 Fluoroacetic acid
Sodium fluoroacetate
Fluoroacetamide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

The general population is not likely to be exposed to methyl fluoroacetate. People who use MFA for work, however, can breathe in or have direct skin contact with the substance.

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