Methoxyacetic acid

Methoxyacetic acid is a derivative of acetic acid in which a hydrogen atom of the methyl group is replaced by a methoxy group. As indicated by the synonym methyl glycolic acid, and as the simplest ether carboxylic acid, methoxyacetic acid can be understood as a methyl ether of glycolic acid.

Methoxyacetic acid
Names
IUPAC name
2-Methoxyacetic acid
Other names
2-Methoxyacetic acid
Methyl glycolic acid
Identifiers
ChEBI
ChemSpider
ECHA InfoCard 100.009.904
EC Number
  • 210-894-6
UNII
Properties
C3H6O3
Molar mass 90.08 g/mol−1
Appearance Clear, colorless, viscous liquid with a pungent odor
Density 1.1768 g/cm−3
Melting point 7–9 °C (45–48 °F; 280–282 K)
Boiling point 202–204 °C (396–399 °F; 475–477 K)
Soluble in water, ethanol, and diethyl ether
Vapor pressure 1.8 mbar (20 °C)
4.8 mbar (50 °C)
Acidity (pKa) 3.57
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Due to its considerable reprotoxic potential, methoxyacetic acid has been adopted into the list of SVHC substances (substances of very high concern) and is only registered as an intermediate product for industrial purposes under strictly controlled conditions.

For consumer applications, such as for the cleaning and decalcification of surfaces, the substance must be substituted by safe alternatives.

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