Methicillin

Methicillin (USAN), also known as meticillin (INN), is a narrow-spectrum β-lactam antibiotic of the penicillin class.

Methicillin
INN: Meticillin
Clinical data
Routes of
administration
IV
ATC code
Pharmacokinetic data
BioavailabilityNot orally absorbed
Metabolismhepatic, 20–40%
Elimination half-life25–60 minutes
Excretionrenal
Identifiers
  • (2S,5R,6R)-6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.460
Chemical and physical data
FormulaC17H20N2O6S
Molar mass380.42 g·mol−1
3D model (JSmol)
  • OC(=O)[C@@H]2N3C(=O)[C@@H](NC(=O)c1c(OC)cccc1OC)[C@H]3SC2(C)C
 NY (what is this?)  (verify)

Methicillin was discovered in 1960.

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