Megakaryocyte

A megakaryocyte (mega- + karyo- + -cyte, "large-nucleus cell") is a large bone marrow cell with a lobated nucleus that produces blood platelets (thrombocytes), which are necessary for normal clotting. In humans, megakaryocytes usually account for 1 out of 10,000 bone marrow cells, but can increase in number nearly 10-fold during the course of certain diseases. Owing to variations in combining forms and spelling, synonyms include megalokaryocyte and megacaryocyte.

Megakaryocyte
Two megakaryocytes in bone marrow, marked with arrows.
Details
LocationBone marrow
FunctionPlatelet production
Identifiers
Latinmegakaryocytur
MeSHD008533
THH2.00.04.3.05003
FMA83555
Anatomical terms of microanatomy
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