Main Line (Pennsylvania Railroad)

The Main Line of the Pennsylvania Railroad was a rail line in Pennsylvania connecting Philadelphia with Pittsburgh via Harrisburg. The rail line was split into two rail lines, and now all of its right-of-way is a cross-state corridor, composed of Amtrak's Philadelphia to Harrisburg Main Line (including SEPTA's Paoli/Thorndale Line service) and the Norfolk Southern Railway's Pittsburgh Line.

For the suburban area west of Philadelphia, see Philadelphia Main Line. For other meanings, see Main Line (disambiguation).
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