Melatonin receptor 1B

MTNR1B
Identifiers
Aliases	MTNR1B, FGQTL2, MEL-1B-R, MT2, Melatonin receptor 1B
External IDs	OMIM: 600804 MGI: 2181726 HomoloGene: 4350 GeneCards: MTNR1B
Gene location (Human)
Chr.	Chromosome 11 (human)
End	92,985,066 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	15,785,852 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; nucleus accumbens; ; placenta; ; caudate nucleus; ; renal cortex; ; endometrium; ; hypothalamus; ; prefrontal cortex; ; temporal lobe; ; urinary bladder;
	Top expressed in
	lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; melatonin receptor activity; protein binding; G protein-coupled receptor activity;
Cellular component	integral component of membrane; membrane; integral component of plasma membrane; plasma membrane;
Biological process	glucose homeostasis; regulation of insulin secretion; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; circadian rhythm; signal transduction; chemical synaptic transmission; G protein-coupled receptor signaling pathway; negative regulation of cGMP-mediated signaling; positive regulation of circadian rhythm; camera-type eye development; negative regulation of neuron apoptotic process; positive regulation of circadian sleep/wake cycle, non-REM sleep; negative regulation of insulin secretion; negative regulation of cytosolic calcium ion concentration; negative regulation of transmission of nerve impulse; positive regulation of transmission of nerve impulse; regulation of neuronal action potential; negative regulation of delayed rectifier potassium channel activity;
	Sources:Amigo / QuickGO
Orthologs
	4544
	244701
	ENSG00000134640
	ENSMUSG00000050901
	P49286
	Q8CIQ6; Q3SXF8
	NM_005959
	NM_145712
	NP_005950
	NP_663758
	Wikidata
View/Edit Human	View/Edit Mouse

Melatonin receptor 1B, also known as MTNR1B, is a protein that in humans is encoded by the MTNR1B gene.

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