MS4A3

MS4A3
Identifiers
Aliases	MS4A3, CD20L, HTM4, membrane spanning 4-domains A3
External IDs	OMIM: 606498 MGI: 2158468 HomoloGene: 4472 GeneCards: MS4A3
Gene location (Human)
Chr.	Chromosome 11 (human)
End	60,071,115 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	11,618,215 bp
RNA expression pattern
	Top expressed in
	bone marrow; ; bone marrow cells; ; monocyte; ; blood; ; spleen; ; right lung; ; placenta; ; appendix; ; upper lobe of left lung; ; gallbladder;
	Top expressed in
	bone marrow; ; right ventricle; ; body of femur; ; olfactory epithelium; ; medial ganglionic eminence; ; spleen; ; cochlea; ; sexually immature organism; ; carotid body; ; digastric muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; perinuclear region of cytoplasm; integral component of membrane; membrane; endomembrane system; plasma membrane; specific granule membrane;
Biological process	regulation of cell cycle; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	932
	170813
	ENSG00000149516; ENSG00000284903
	ENSMUSG00000024681
	Q96HJ5
	Q920C4
	NM_001031666; NM_001031809; NM_006138
	NM_133246
	NP_001026836; NP_001026979; NP_006129
	NP_573509
	Wikidata
View/Edit Human	View/Edit Mouse

Membrane-spanning 4-domains subfamily A member 3 is a protein that in humans is encoded by the MS4A3 gene.

This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.