MCM2

MCM2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UUZ, 5BNV, 5BNX, 5BO0, 5C3I, 5JA4
Identifiers
Aliases	MCM2, BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19, minichromosome maintenance complex component 2, DFNA70
External IDs	OMIM: 116945 MGI: 105380 HomoloGene: 3325 GeneCards: MCM2
Gene location (Human)
Chr.	Chromosome 3 (human)
End	127,622,436 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	88,875,762 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; embryo; ; ganglionic eminence; ; spongy bone; ; bone marrow cells; ; appendix; ; stromal cell of endometrium; ; hair follicle; ; placenta;
	Top expressed in
	maxillary prominence; ; somite; ; primitive streak; ; Paneth cell; ; yolk sac; ; abdominal wall; ; thymus; ; ureter; ; endocardial cushion; ; secondary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; nucleotide binding; helicase activity; histone binding; metal ion binding; DNA helicase activity; protein binding; enzyme binding; DNA replication origin binding; hydrolase activity; ATP binding; single-stranded DNA binding; single-stranded DNA helicase activity; 3'-5' DNA helicase activity;
Cellular component	cytoplasm; microtubule cytoskeleton; nucleoplasm; nuclear origin of replication recognition complex; chromatin; MCM complex; nucleus; cytosol; nucleolus;
Biological process	cellular response to interleukin-4; nucleosome assembly; G1 phase; DNA replication; DNA replication initiation; DNA unwinding involved in DNA replication; apoptotic process; cell cycle; cochlea development; G1/S transition of mitotic cell cycle; negative regulation of DNA helicase activity; double-strand break repair via break-induced replication; pre-replicative complex assembly involved in nuclear cell cycle DNA replication; mitotic DNA replication initiation;
	Sources:Amigo / QuickGO
Orthologs
	4171
	17216
	ENSG00000073111
	ENSMUSG00000002870
	P49736
	P97310
	NM_004526
	NM_008564
	NP_004517
	NP_032590
	Wikidata
View/Edit Human	View/Edit Mouse

DNA replication licensing factor MCM2 is a protein that in humans is encoded by the MCM2 gene.

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