Locus coeruleus
The locus coeruleus (/sɪˈruːliəs/) (LC), also spelled locus caeruleus or locus ceruleus, is a nucleus in the pons of the brainstem involved with physiological responses to stress and panic. It is a part of the reticular activating system.
| Locus coeruleus | |
|---|---|
Rhomboid fossa. (Locus coeruleus not labeled, but is very near [just lateral to] the colliculus facialis, which is labeled at center left.) | |
Micrograph showing the locus coeruleus. HE-LFB stain. | |
| Details | |
| Identifiers | |
| Latin | locus caeruleus ("blue place") |
| MeSH | D008125 |
| NeuroNames | 583 |
| NeuroLex ID | birnlex_905 |
| TA98 | A14.1.05.436 A14.1.05.706 |
| TA2 | 5944 |
| FMA | 72478 |
| Anatomical terms of neuroanatomy | |
The locus coeruleus, which in Latin means "blue spot", is the principal site for brain synthesis of norepinephrine (noradrenaline). The locus coeruleus and the areas of the body affected by the norepinephrine it produces are described collectively as the locus coeruleus-noradrenergic system or LC-NA system. Norepinephrine may also be released directly into the blood from the adrenal medulla.
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