Liver failure

Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). Recently, a third form of liver failure known as acute-on-chronic liver failure (ACLF) is increasingly being recognized.

Liver failure
Other namesHepatic insufficiency, liver dysfunction
A person with massive ascites and caput medusae due to cirrhotic liver failure
SpecialtyGastroenterology, hepatology 
Symptomsabdominal inflammation, fluid retention, hyperglycemia, nausea, vomiting, jaundice, acute or chronic fatigue, hyponatremia, hypokalemia, respiratory alkalosis, metabolic acidosis, bilirubinuria, glycosuria, pruritus
Risk factorsExcessive consumption of alcohol, fatty foods; obesity; Type 2 Diabetes; sharing or reusing syringes; having tattoos or body piercings
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