LEFTY2

LEFTY2
Identifiers
Aliases	LEFTY2, EBAF, LEFTA, LEFTYA, TGFB4, left-right determination factor 2
External IDs	OMIM: 601877 MGI: 2443573 HomoloGene: 2434 GeneCards: LEFTY2
Gene location (Human)
Chr.	Chromosome 1 (human)
End	225,941,383 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	180,726,668 bp
RNA expression pattern
	Top expressed in
	myometrium; ; sperm; ; canal of the cervix; ; ascending aorta; ; right coronary artery; ; popliteal artery; ; caput epididymis; ; smooth muscle tissue; ; left coronary artery; ; anterior pituitary;
	Top expressed in
	mesoderm; ; neural plate; ; primitive streak; ; inner cell mass; ; blastocyst; ; hippocampal formation; ; hippocampus proper; ; floor plate; ; ascending aorta; ; testicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	transforming growth factor beta receptor binding; cytokine activity; growth factor activity;
Cellular component	extracellular matrix; extracellular region; platelet alpha granule lumen; extracellular space; collagen-containing extracellular matrix;
Biological process	multicellular organism development; regulation of apoptotic process; positive regulation of pathway-restricted SMAD protein phosphorylation; cell growth; platelet degranulation; regulation of MAPK cascade; transforming growth factor beta receptor signaling pathway; SMAD protein signal transduction; cell development; BMP signaling pathway; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	7044
	320202
	ENSG00000143768
	ENSMUSG00000066652
	O00292
	P57785
	NM_001172425; NM_003240
	NM_177099
	NP_001165896; NP_003231
	NP_796073
	Wikidata
View/Edit Human	View/Edit Mouse

Left-right determination factor 2 is a protein that in humans is encoded by the LEFTY2 gene.

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