KCNA2

KCNA2
Identifiers
Aliases	KCNA2, HBK5, HK4, HUKIV, KV1.2, MK2, NGK1, RBK2, EIEE32, potassium voltage-gated channel subfamily A member 2, DEE32
External IDs	OMIM: 176262 MGI: 96659 HomoloGene: 21034 GeneCards: KCNA2
Gene location (Human)
Chr.	Chromosome 1 (human)
End	110,631,474 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	107,022,321 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; middle temporal gyrus; ; postcentral gyrus; ; cerebellar vermis; ; superior frontal gyrus; ; pons; ; Brodmann area 46; ; endothelial cell; ; trigeminal ganglion; ; entorhinal cortex;
	Top expressed in
	lateral geniculate nucleus; ; pontine nuclei; ; medial geniculate nucleus; ; anterior horn of spinal cord; ; medial vestibular nucleus; ; medial dorsal nucleus; ; cerebellar vermis; ; facial motor nucleus; ; habenula; ; dorsal tegmental nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	potassium channel activity; voltage-gated ion channel activity; ion channel activity; protein binding; voltage-gated potassium channel activity; delayed rectifier potassium channel activity; outward rectifier potassium channel activity; kinesin binding;
Cellular component	juxtaparanode region of axon; axon terminus; integral component of membrane; perikaryon; cell projection; endoplasmic reticulum membrane; membrane; voltage-gated potassium channel complex; plasma membrane; synapse; integral component of plasma membrane; neuronal cell body membrane; axon; cell junction; dendrite; endoplasmic reticulum; neuron projection; lamellipodium membrane; presynaptic membrane; lamellipodium; potassium channel complex; paranodal junction; calyx of Held; integral component of presynaptic membrane;
Biological process	regulation of dopamine secretion; regulation of ion transmembrane transport; ion transport; optic nerve structural organization; potassium ion transport; transmembrane transport; potassium ion transmembrane transport; regulation of circadian sleep/wake cycle, non-REM sleep; protein homooligomerization; protein complex oligomerization; sensory perception of pain; neuronal action potential;
	Sources:Amigo / QuickGO
Orthologs
	3737
	16490
	ENSG00000177301
	ENSMUSG00000040724
	P16389
	P63141
	NM_001204269; NM_004974
	NM_008417
	NP_001191198; NP_004965
	NP_032443
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily A member 2 also known as K_v1.2 is a protein that in humans is encoded by the KCNA2 gene.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.