Dolutegravir/rilpivirine

Dolutegravir/rilpivirine, sold under the brand name Juluca, is a fixed-dose combination antiretroviral medication for the treatment of HIV/AIDS. It contains the medicines dolutegravir and rilpivirine. It is taken by mouth.

Dolutegravir/rilpivirine
Combination of
DolutegravirHIV integrase strand transfer inhibitor (INSTI)
RilpivirineHIV non-nucleoside reverse-transcriptase inhibitor (NNRTI)
Clinical data
Trade namesJuluca
AHFS/Drugs.comMonograph
License data
Pregnancy
category
  • AU: B1
Routes of
administration		By mouth
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
  • CA: ℞-only
  • UK: POM (Prescription only)
  • US: ℞-only
  • EU: Rx-only
  • In general: ℞ (Prescription only)
Identifiers
KEGG

The most common adverse reactions (of all severity grades) are diarrhea and headache.

Dolutegravir/rilpivirine was approved for use in the United States in November 2017, and for use in the European Union in May 2018.

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