JWH-122

JWH-122 is a synthetic cannabimimetic that was discovered by John W. Huffman. It is a methylated analogue of JWH-018. It has a Ki of 0.69 nM at CB1 and 1.2 nM at CB2.

JWH-122
Legal status
Legal status
Identifiers
  • (4-Methyl-1-naphthyl)-(1-pentylindol-3-yl)methanone
CAS Number
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC25H25NO
Molar mass355.481 g·mol−1
3D model (JSmol)
  • CCCCCn1cc(c2c1cccc2)C(=O)c3ccc(c4c3cccc4)C
  • InChI=1S/C25H25NO/c1-3-4-9-16-26-17-23(21-12-7-8-13-24(21)26)25(27)22-15-14-18(2)19-10-5-6-11-20(19)22/h5-8,10-15,17H,3-4,9,16H2,1-2H3 Y
  • Key:HUKJQMKQFWYIHS-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

In January 2015, over 40 people were reportedly sickened after eating a holiday bread called Rosca de reyes purchased at a bakery in Santa Ana, California, that was laced with JWH-122.

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