JWH-030

JWH-030 is a research chemical which is a cannabinoid receptor agonist. It has analgesic effects and is used in scientific research. It is a partial agonist at CB1 receptors, with a Ki of 87 nM, making it roughly half the potency of THC. It was discovered and named after John W. Huffman.

JWH-030
Legal status
Legal status
Identifiers
  • Naphthalen-1-yl-(1-pentylpyrrol-3-yl)methanone
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H21NO
Molar mass291.394 g·mol−1
3D model (JSmol)
  • CCCCCn3cc(cc3)C(=O)c1cccc2ccccc12
  • InChI=1S/C20H21NO/c1-2-3-6-13-21-14-12-17(15-21)20(22)19-11-7-9-16-8-4-5-10-18(16)19/h4-5,7-12,14-15H,2-3,6,13H2,1H3
  • Key:VPBJQDBKZSHCPC-UHFFFAOYSA-N
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In the United States, CB1 receptor agonists of the 3-(1-naphthoyl)pyrrole class such as JWH-030 are Schedule I Controlled Substances.

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