Iotalamic acid

Iotalamic acid, sold under the brand name Conray, is an iodine-containing radiocontrast agent. It is available in form of its salts, sodium iotalamate and meglumine iotalamate. It can be given intravenously or intravesically (into the urinary bladder).

Iotalamic acid
Clinical data
Trade namesConray, Glofil-125, Cysto-Conray II, others
Other namesMI-216, iothalamate meglumine, Iothalamic acid (USAN US)
AHFS/Drugs.comConsumer Drug Information
License data
Routes of
administration
Intravascular
ATC code
Legal status
Legal status
Identifiers
  • 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.017.181
Chemical and physical data
FormulaC11H9I3N2O4
Molar mass613.916 g·mol−1
3D model (JSmol)
  • CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I
  • InChI=1S/C11H9I3N2O4/c1-3(17)16-9-7(13)4(10(18)15-2)6(12)5(8(9)14)11(19)20/h1-2H3,(H,15,18)(H,16,17)(H,19,20)
  • Key:UXIGWFXRQKWHHA-UHFFFAOYSA-N

A radioactive formulation is also available as sodium iothalamate I-125 injection (brand name Glofil-125). It is indicated for evaluation of glomerular filtration in the diagnosis or monitoring of people with kidney disease.

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