ITPKA

ITPKA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1W2C, 1W2D, 1W2F, 4UPU
Identifiers
Aliases	ITPKA, IP3-3KA, IP3KA, inositol-trisphosphate 3-kinase A
External IDs	OMIM: 147521 MGI: 1333822 HomoloGene: 1671 GeneCards: ITPKA
Gene location (Human)
Chr.	Chromosome 15 (human)
End	41,503,551 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	119,581,744 bp
RNA expression pattern
	Top expressed in
	Brodmann area 9; ; prefrontal cortex; ; middle temporal gyrus; ; caudate nucleus; ; putamen; ; cingulate gyrus; ; nucleus accumbens; ; Brodmann area 46; ; superior frontal gyrus; ; amygdala;
	Top expressed in
	Region I of hippocampus proper; ; hippocampus proper; ; prefrontal cortex; ; superior frontal gyrus; ; temporal lobe; ; nucleus accumbens; ; amygdala; ; subiculum; ; primary motor cortex; ; cingulate gyrus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calmodulin-dependent protein kinase activity; transferase activity; nucleotide binding; inositol-1,4,5-trisphosphate 3-kinase activity; ATP binding; calmodulin binding; kinase activity;
Cellular component	cytosol; dendritic spine;
Biological process	dendritic spine maintenance; protein phosphorylation; inositol phosphate metabolic process; positive regulation of dendritic spine morphogenesis; actin cytoskeleton organization; inositol metabolic process; phosphorylation; signal transduction; regulation of synaptic plasticity; inositol phosphate biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	3706
	228550
	ENSG00000137825
	ENSMUSG00000027296
	P23677
	Q8R071
	NM_002220
	NM_146125
	NP_002211
	NP_666237
	Wikidata
View/Edit Human	View/Edit Mouse

Inositol-trisphosphate 3-kinase A is an enzyme that in humans is encoded by the ITPKA gene.

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