INSL4

INSL4
Identifiers
Aliases	INSL4, EPIL, PLACENTIN, insulin like 4
External IDs	OMIM: 600910 HomoloGene: 88662 GeneCards: INSL4
Gene location (Human)
Chr.	Chromosome 9 (human)
End	5,235,304 bp
RNA expression pattern
	Top expressed in
	placenta; ; corpus epididymis; ; stromal cell of endometrium; ; cecum; ; appendix; ; liver; ; smooth muscle tissue; ; right lobe of liver; ; popliteal artery; ; sigmoid colon;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signaling receptor binding; insulin-like growth factor receptor binding; hormone activity;
Cellular component	extracellular region; extracellular space;
Biological process	multicellular organism development; female pregnancy; cell-cell signaling; cell population proliferation; signal transduction; regulation of signaling receptor activity; positive regulation of chorionic trophoblast cell proliferation;
	Sources:Amigo / QuickGO
Orthologs
	3641
	n/a
	ENSG00000120211
	n/a
	Q14641
	n/a
	NM_002195
	n/a
	NP_002186
	n/a
	Wikidata
View/Edit Human

Early placenta insulin-like peptide is a protein that in humans is encoded by the INSL4 gene.

INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast.

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