IFNA2

IFNA2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1RH2, 3S9D, 1ITF, 2LAG, 4YPG, 2KZ1, 2HYM, 2LMS, 3SE3, 4Z5R
Identifiers
Aliases	IFNA2, IFN-alphaA, IFNA, IFNA2B, INFA2, interferon, alpha 2, interferon alpha 2, IFN-alpha-2, leIF A
External IDs	OMIM: 147562 MGI: 107666 HomoloGene: 86655 GeneCards: IFNA2
Gene location (Human)
Chr.	Chromosome 9 (human)
End	21,385,398 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	88,602,149 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; putamen; ; Achilles tendon; ; hippocampus proper; ; caudate nucleus; ; temporal lobe; ; amygdala; ; mesencephalon; ; substantia nigra; ; frontal lobe;
	Top expressed in
	lacrimal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cytokine activity; type I interferon receptor binding; protein binding; cytokine receptor binding;
Cellular component	extracellular region; extracellular space; collagen-containing extracellular matrix;
Biological process	apoptotic process; defense response; negative regulation of viral entry into host cell; response to exogenous dsRNA; cell-cell signaling; negative regulation of T-helper 2 cell cytokine production; blood coagulation; positive regulation of peptidyl-serine phosphorylation of STAT protein; negative regulation of gene expression; positive regulation of transcription, DNA-templated; natural killer cell activation involved in immune response; cell surface receptor signaling pathway; B cell proliferation; humoral immune response; type I interferon signaling pathway; B cell differentiation; positive regulation of phosphorylation; inflammatory response; negative regulation of transcription, DNA-templated; negative regulation of T cell differentiation; T cell activation involved in immune response; defense response to virus; innate immune response; cytokine-mediated signaling pathway; positive regulation of tyrosine phosphorylation of STAT protein; regulation of signaling receptor activity; adaptive immune response;
	Sources:Amigo / QuickGO
Orthologs
	3440
	15965
	ENSG00000188379
	ENSMUSG00000078354
	P01563
	P01573
	NM_000605
	NM_010503
	NP_000596
	NP_034633
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon alpha-2 is a protein that in humans is encoded by the IFNA2 gene.

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