Humanin

MT-RNR2
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	1Y32, 2GD3, 5GIW
Identifiers
Aliases	RNR2, mitochondrially encoded 16S RNA, MTRNR2
External IDs	OMIM: 561010 MGI: 102492 GeneCards: RNR2
Gene ontology
Molecular function	signaling receptor binding; protein binding; receptor antagonist activity;
Cellular component	cytoplasm; perinuclear region of cytoplasm; extracellular region; mitochondrion;
Biological process	negative regulation of apoptotic process; leukocyte chemotaxis; cellular iron ion homeostasis; apoptotic process; extracellular negative regulation of signal transduction; G protein-coupled receptor signaling pathway; negative regulation of execution phase of apoptosis; negative regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	4550
	17725
	ENSG00000210082
	ENSMUSG00000064339
	Q8IVG9
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Humanin is a micropeptide encoded in the mitochondrial genome by the 16S ribosomal RNA gene, MT-RNR2. Its structure contains a three-turn α-helix, and no symmetry.

In in vitro and animal models, it appears to have cytoprotective effects.

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