Heat shock protein 47

SERPINH1
Identifiers
Aliases	SERPINH1, AsTP3, CBP1, CBP2, HSP47, OI10, PIG14, PPROM, RA-A47, SERPINH2, gp46, serpin family H member 1
External IDs	OMIM: 600943 MGI: 88283 HomoloGene: 20331 GeneCards: SERPINH1
Gene location (Human)
Chr.	Chromosome 11 (human)
End	75,572,783 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	99,002,446 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; smooth muscle tissue; ; pericardium; ; right coronary artery; ; ascending aorta; ; left uterine tube; ; upper lobe of left lung; ; myometrium; ; left coronary artery; ; canal of the cervix;
	Top expressed in
	dermis; ; molar; ; ascending aorta; ; calvaria; ; aortic valve; ; atrium; ; body of femur; ; belly cord; ; hand; ; maxillary prominence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	unfolded protein binding; collagen binding; RNA binding; serine-type endopeptidase inhibitor activity;
Cellular component	cytoplasm; membrane raft; endoplasmic reticulum lumen; extracellular exosome; endoplasmic reticulum-Golgi intermediate compartment; extracellular space; endoplasmic reticulum; collagen-containing extracellular matrix;
Biological process	response to unfolded protein; protein maturation; chondrocyte development involved in endochondral bone morphogenesis; collagen biosynthetic process; collagen fibril organization; negative regulation of endopeptidase activity;
	Sources:Amigo / QuickGO
Orthologs
	871
	12406
	ENSG00000149257
	ENSMUSG00000070436
	P50454
	P19324
	NM_001207014; NM_001235
	NM_001111043; NM_001111044; NM_009825; NM_001285776
	NP_001193943; NP_001226
	NP_001104513; NP_001104514; NP_001272705; NP_033955
	Wikidata
View/Edit Human	View/Edit Mouse

Heat shock protein 47, also known as SERPINH1 is a serpin which serves as a human chaperone protein for collagen.

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