GTF3A

GTF3A
Identifiers
Aliases	GTF3A, AP2, TFIIIA, general transcription factor IIIA
External IDs	OMIM: 600860 MGI: 1913846 HomoloGene: 55630 GeneCards: GTF3A
Gene location (Human)
Chr.	Chromosome 13 (human)
End	27,435,823 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	146,892,424 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; right ventricle; ; middle temporal gyrus; ; biceps brachii; ; thoracic diaphragm; ; palpebral conjunctiva; ; body of tongue; ; gastrocnemius muscle; ; left ventricle; ; triceps brachii muscle;
	Top expressed in
	otic placode; ; saccule; ; abdominal wall; ; primitive streak; ; neural tube; ; renal corpuscle; ; external carotid artery; ; internal carotid artery; ; medial ganglionic eminence; ; vas deferens;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleic acid binding; DNA binding; metal ion binding; RNA binding; 5S rRNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm;
Biological process	rRNA transcription; regulation of transcription, DNA-templated; transcription, DNA-templated; transcription by RNA polymerase III; ribosomal large subunit biogenesis; ribosome biogenesis; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	2971
	66596
	ENSG00000122034
	ENSMUSG00000016503
	Q92664
	Q8VHT7
	NM_002097
	NM_025652
	NP_002088
	NP_079928
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor IIIA is a protein that in humans is encoded by the GTF3A gene.

It was first purified and identified as the first mammalian gene-specific activator by Roeder in 1980, and later characterized by Wolffe and Brown in 1988.

The TFIIIA in Xenopus was the first zinc finger protein discovered.

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