GRID1

GRID1
Identifiers
Aliases	GRID1, GluD1, glutamate ionotropic receptor delta type subunit 1, GluD1-b
External IDs	OMIM: 610659 MGI: 95812 HomoloGene: 69017 GeneCards: GRID1
Gene location (Human)
Chr.	Chromosome 10 (human)
End	86,366,795 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	35,305,336 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; nucleus accumbens; ; putamen; ; caudate nucleus; ; hypothalamus; ; substantia nigra; ; external globus pallidus; ; amygdala; ; cingulate gyrus; ; Brodmann area 9;
	Top expressed in
	Region I of hippocampus proper; ; nucleus accumbens; ; dorsomedial hypothalamic nucleus; ; entorhinal cortex; ; superior frontal gyrus; ; substantia nigra; ; subiculum; ; lateral hypothalamus; ; inferior colliculus; ; superior colliculus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ion channel activity; extracellularly glutamate-gated ion channel activity; ionotropic glutamate receptor activity; glutamate receptor activity; signaling receptor activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential;
Cellular component	integral component of membrane; cell junction; postsynaptic membrane; plasma membrane; synapse; extracellular exosome; membrane; glutamatergic synapse; integral component of postsynaptic density membrane;
Biological process	social behavior; ion transmembrane transport; ionotropic glutamate receptor signaling pathway; ion transport; excitatory postsynaptic potential; transport; synaptic transmission, glutamatergic; modulation of chemical synaptic transmission; regulation of postsynaptic membrane potential;
	Sources:Amigo / QuickGO
Orthologs
	2894
	14803
	ENSG00000182771
	ENSMUSG00000041078
	Q9ULK0
	Q61627
	NM_017551
	NM_008166
	NP_060021
	NP_032192
	Wikidata
View/Edit Human	View/Edit Mouse

Glutamate receptor delta-1 subunit also known as GluD1 or GluRδ1 is a transmembrane protein (1009 aa) encoded by the GRID1 gene. A C-terminal GluD1 splicing isoform (896 aa) has been described based on mRNA analysis.

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